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San Francisco 49ers vs Seattle Seahawks NFL match analysis, predictions and odds

In the Wild Card round of the NFL playoffs, the San Francisco 49ers (13-4) will face off against the Seattle Seahawks (9-8) on Saturday. The Seattle Seahawks clinched a playoff berth by taking the seventh and final NFC wild card spot, setting up a road matchup with the second-seeded NFC West champions San Francisco 49ers. The San Francisco 49ers have won their past two games against the Seattle Seahawks. With that kind of recent history in mind, it’s easy to see why they’re confident about reaching the divisional round. On the other side, a Seattle Seahawks win will propel the visitors into the second round of playoffs, giving them a good chance at going all the way.

Form San Francisco 49ers

The San Francisco 49ers signed off on the regular season by beating the Arizona Cardinals 38-13 to make it ten wins in a row, leaving them 10-0 in their last 10 matches.

Playing at the Levi’s Stadium brings out the best in the San Francisco 49ers. They have the sixth-best home offensive record, averaging 28.0 points per game with home-field advantage and 26.5 points for all 17 of their regular season games. Visiting offenses normally struggle to break down the hosts’ defense, which has the first-best defensive record at home, having only allowed 14.8 points on their own turf and 16.3 points in all outings.

The San Francisco 49ers earned the right to be in the playoffs after a 13-4 season. The hosts finished first in the NFC West and took the second seed in the NFC. While it will be nothing easy, they hope to have a deep postseason run.

Form Seattle Seahawks

The Seattle Seahawks have a knack for beating NFC West teams, having won four of their last five divisional matchups. They ended the regular season with a 19-16 victory over the Los Angeles Rams, leaving them 5-5 in the last ten games.

It’s been a rough few weeks for the visiting offense in terms of points scored. In the last five matches, the Seattle Seahawks have only put up 17.8 points on average which is way below their season average of 23.9 points. On the other side, the defense has struggled to contain opposing offenses, giving up 23.6 points per game this year.

Expectations aren’t high for the Seattle Seahawks going into the playoffs. The hosts clinched a postseason berth by taking the seventh seed in the NFC Conference, finishing second in the NFC West, but chances of a deep postseason run appear to be a long shot.


The San Francisco 49ers came away with a 13-21 win in their previous encounter with the Seattle Seahawks at the Lumen Field on December 2022. In the last ten NFC West matchups of this series, the Seattle Seahawks came out on top more often than not. The away team claimed six wins against the San Francisco 49ers, leaving them with an overall record of 6-4.

In their past ten head-to-head games, the San Francisco 49ers pulled off 23.4 points on average per game, whereas Seattle Seahawks managed 25.5 points per match.


Seattle Seahawks at San Francisco 49ers odds

Odds for Seattle Seahawks vs San Francisco 49ers is Provided by Bet365. For a full list of odds for the match visit Bet365.com

  • Moneyline (ML): Seattle Seahawks (+400) | San Francisco 49ers (-526)
  • Against the spread (ATS): Seattle Seahawks +9.5 (-110) | San Francisco 49ers -9.5 (-110)
  • Over/Under (O/U): 42.5 (-110) | (-110)

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Go for the San Francisco 49ers to win (1.19) as your winning pick for the moneyline.

The San Francisco 49ers enter this matchup riding a two-match winning streak against the Seattle Seahawks. Oddsmakers rate their chances of another victory in this series at 84%, pricing a home win at -526 on the moneyline. The Seattle Seahawks have struggled recently; they’ve lost three of their past five games, and it’s unlikely that they will improve upon their current win total of nine as visitors to Levi’s Stadium on Saturday.

The San Francisco 49ers have rallied off ten straight wins, so it’s no surprise that they are favored over Seattle Seahawks. The Seattle Seahawks have struggled on defense, allowing an average of 23.6 points per game which may justify a spread as high as-9.5

Against the Spread

Betting on the San Francisco 49ers -9.5 (1.91) is our favorite play for this matchup.

The oddsmakers have predicted that the San Francisco 49ers will win this matchup against the Seattle Seahawks by more than a touchdown. The current betting line puts the home team as the 9.5-point favorite over its opponent. A winning margin as high as 9.0 points has settled the last five matches between the San Francisco 49ers and Seattle Seahawks.

In their most recent games against NFC West opponents, the San Francisco 49ers went 9-4 ATS. Their offense managed 19.9 points per game in that stretch, while the defense gave up 20.2 points on average. The San Francisco 49ers are specialists in covering the spread and have the stats to prove it. They have covered the spread in their past five home matches and are 8-2 ATS in the last 10 overall.

On the other side of the field, the Seattle Seahawks have failed to cover the spread in the last three matches played on the road. In their past 10 matches, the Seattle Seahawks went 3-7 ATS and ended up 4-6 ATS from their ten most recent road trips.


Total over 42.5 (1.91) is your best bet for this game.

The total may have passed the 45-point mark, but it didn’t quite go above 50 points, as the last ten games between the San Francisco 49ers and the Seattle Seahawks produced an average of 48.9 points.

The total went higher than expected in eight of these past ten contests. Over was the smart bet five out of ten times at the Levi’s Stadium. For Saturday’s matchup, the current total sits at 42.5 points.

In their most recent NFC West matchups at the Levi’s Stadium, the San Francisco 49ers averaged 39.9 points points per game and went 2-4 against the total. The San Francisco 49ers have seen four of the past five home games going over. In fact, when looking back on their last 10 matches (both at home and away), they are 7-3 in the over and under betting line.

The total has gone under in four of the Seattle Seahawks’s last five games, during which they have averaged 47.5 points per game this season. Over was a winning bet three times in the past five road games for the Seattle Seahawks, who are 4-6 against the total in their last ten home and away games combined.

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